ParkinsonCanadaV1, Main, Exploration, bibRecord, 000951

Randomized trial of IPX066, carbidopa/levodopa extended release, in early Parkinson's disease.

Identifieur interne : 000951 ( Main/Exploration ); précédent : 000950; suivant : 000952

Randomized trial of IPX066, carbidopa/levodopa extended release, in early Parkinson's disease.

Auteurs : Rajesh Pahwa [États-Unis] ; Kelly E. Lyons [États-Unis] ; Robert A. Hauser [États-Unis] ; Stanley Fahn [États-Unis] ; Joseph Jankovic [États-Unis] ; Emmanuelle Pourcher [Canada] ; Ann Hsu [États-Unis] ; Martin O'Connell [États-Unis] ; Sherron Kell [États-Unis] ; Suneel Gupta [États-Unis]

Source :

Parkinsonism & related disorders [ 1873-5126 ] ; 2014.

RBID : pubmed:24055014

English descriptors

KwdEn :
- Aged, Antiparkinson Agents (administration & dosage), Antiparkinson Agents (adverse effects), Carbidopa (administration & dosage), Carbidopa (adverse effects), Dose-Response Relationship, Drug, Double-Blind Method, Drug Combinations, Female, Humans, Levodopa (administration & dosage), Levodopa (adverse effects), Levodopa (metabolism), Male, Middle Aged, Parkinson Disease (drug therapy), Parkinson Disease (metabolism), Treatment Outcome.
MESH :
- chemical , administration & dosage : Antiparkinson Agents, Carbidopa, Levodopa.
- chemical , adverse effects : Antiparkinson Agents, Carbidopa, Levodopa.
- chemical , metabolism : Levodopa.
- drug therapy : Parkinson Disease.
- metabolism : Parkinson Disease.
- Aged, Dose-Response Relationship, Drug, Double-Blind Method, Drug Combinations, Female, Humans, Male, Middle Aged, Treatment Outcome.

Abstract

IPX066 is an extended release carbidopa/levodopa formulation designed to rapidly attain and maintain therapeutic plasma concentrations for a prolonged duration, allowing dosing intervals of approximately 6 h. The objective was to assess the efficacy, safety, and impact on quality of life of IPX066 in the treatment of levodopa-naive Parkinson's disease (PD) patients.

DOI: 10.1016/j.parkreldis.2013.08.017
PubMed: 24055014

Affiliations:

Le document en format XML

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<term>Carbidopa (administration & dosage)</term>
<term>Carbidopa (adverse effects)</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Drug Combinations</term>
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<term>Levodopa (adverse effects)</term>
<term>Levodopa (metabolism)</term>
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<term>Middle Aged</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (metabolism)</term>
<term>Treatment Outcome</term>
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<term>Carbidopa</term>
<term>Levodopa</term>
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<term>Carbidopa</term>
<term>Levodopa</term>
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<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Drug Combinations</term>
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<front><div type="abstract" xml:lang="en">IPX066 is an extended release carbidopa/levodopa formulation designed to rapidly attain and maintain therapeutic plasma concentrations for a prolonged duration, allowing dosing intervals of approximately 6 h. The objective was to assess the efficacy, safety, and impact on quality of life of IPX066 in the treatment of levodopa-naive Parkinson's disease (PD) patients.</div>
</front>
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<name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
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<name sortKey="Lyons, Kelly E" sort="Lyons, Kelly E" uniqKey="Lyons K" first="Kelly E" last="Lyons">Kelly E. Lyons</name>
<name sortKey="O Connell, Martin" sort="O Connell, Martin" uniqKey="O Connell M" first="Martin" last="O'Connell">Martin O'Connell</name>
</country>
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La maladie de Parkinson au Canada (serveur d'exploration)

Randomized trial of IPX066, carbidopa/levodopa extended release, in early Parkinson's disease.

Randomized trial of IPX066, carbidopa/levodopa extended release, in early Parkinson's disease.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.